Scientific Publications 2016 [View all on PubMed]

1. Agnandji ST, Huttner A, Zinser ME, Njuguna P, Dahlke C, Fernandes JF, Yerly S, Dayer JA, Kraehling V, Kasonta R, Adegnika AA, Altfeld M, Auderset F, Bache EB, Biedenkopf N, Borregaard S, Brosnahan JS, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling SK, Finckh A, Goncalves AR, Grobusch MP, Hooper J, Jambrecina A, Kabwende AL, Kaya G, Kimani D, Lell B, Lemaître B, Lohse AW, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl FR, Staines HM, Strecker T, Stubbe HC, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny MP, Bejon P, Kremsner PG, Addo MM, Siegrist CA. Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe. N Engl J Med. 2016 Apr 28;374(17):1647-60. [Abstract]
2. Alabi AS, Traoré AN, Loembe MM, Ateba-Ngoa U, Frank M, Adegnika AA, Lell B, Mahoumbou J, Köhler C, Kremsner PG, Grobusch MP; CERMEL TB CapDev Group. Enhanced laboratory capacity development: a boost for effective tuberculosis control in resource-limited settings. Int J Infect Dis. 2017 Mar;56:81-84. [Abstract]
3. Ateba-Ngoa U, Jones S, Zinsou JF, Honkpehedji J, Adegnika AA, Agobe JC, Massinga-Loembe M, Mordmüller B, Bousema T, Yazdanbakhsh M. Associations Between Helminth Infections, Plasmodium falciparum Parasite Carriage and Antibody Responses to Sexual and Asexual Stage Malarial Antigens. Am J Trop Med Hyg. 2016 Aug 3;95(2):394-400. [Abstract] [Free Full Article]
4. Bélard S, Remppis J, Bootsma S, Janssen S, Kombila DU, Beyeme JO, Rossatanga EG, Kokou C, Osbak KK, Obiang Mba RM, Kaba HM, Traoré AN, Ehrhardt J, Bache EB, Flamen A, Rüsch-Gerdes S, Frank M, Adegnika AA, Lell B, Niemann S, Kremsner PG, Loembé MM, Alabi AS, Grobusch MP. Tuberculosis Treatment Outcome and Drug Resistance in Lambaréné, Gabon: A Prospective Cohort Study. Am J Trop Med Hyg. 2016 Aug 3;95(2):472-80. [Abstract] [Free Full Article]
5. Brückner S, Agnandji ST, Elias J, Berberich S, Bache E, Fernandes J, Loembe MM, Hass J, Lell B, Mordmüller B, Adegnika AA, Kremsner P, Esen M. A single-dose antihelminthic treatment does not influence immunogenicity of a meningococcal and a cholera vaccine in Gabonese school children. Vaccine. 2016 Oct 17;34(44):5384-5390. [Abstract]
6. Bruske EI, Dimonte S, Enderes C, Tschan S, Flötenmeyer M, Koch I, Berger J, Kremsner P, Frank M. In Vitro Variant Surface Antigen Expression in Plasmodium falciparum Parasites from a Semi-Immune Individual Is Not Correlated with Var Gene Transcription. PLoS One. 2016 Dec 1;11(12):e0166135. [Abstract] [Free Full Article]
7. Burger RJ, Visser BJ, Grobusch MP, van Vugt M. The influence of pregnancy on the pharmacokinetic properties of artemisinin combination therapy (ACT): a systematic review. Malar J. 2016 Feb 18;15(1):99. [Abstract] [Free Full Article]
8. de Jong SE, Selman MH, Adegnika AA, Amoah AS, van Riet E, Kruize YC, Raynes JG, Rodriguez A, Boakye D, von Mutius E, Knulst AC, Genuneit J, Cooper PJ, Hokke CH, Wuhrer M, Yazdanbakhsh M. IgG1 Fc N-glycan galactosylation as a biomarker for immune activation. Sci Rep. 2016 Jun 16;6:28207. [Abstract] [Free Full Article]
9. Ehrhardt J, Alabi AS, Kremsner PG, Rabsch W, Becker K, Foguim FT, Kuczius T, Esen M, Schaumburg F. Bacterial contamination of water samples in Gabon, 2013. J Microbiol Immunol Infect. 2016 May 13. pii: S1684-1182(16)30035-4. [Abstract]
10. Gabor JJ, Schwarz NG, Esen M, Kremsner PG, Grobusch MP. Dengue and chikungunya seroprevalence in Gabonese infants prior to major outbreaks in 2007 and 2010: A sero-epidemiological study. Travel Med Infect Dis. 2016 Jan-Feb;14(1):26-31. [Abstract]
11. Guggisberg AM, Sundararaman SA, Lanaspa M, Moraleda C, González R, Mayor A, Cisteró P, Hutchinson D, Kremsner PG, Hahn BH, Bassat Q, Odom AR. Whole-Genome Sequencing to Evaluate the Resistance Landscape Following Antimalarial Treatment Failure With Fosmidomycin-Clindamycin. J Infect Dis. 2016 Oct 1;214(7):1085-91. [Abstract] [Free Full Article]
12. Heinemann P, Tia M, Alabi A, Anon JC, Auste B, Essbauer S, Gnionsahe A, Kigninlman H, Klempa B, Kraef C, Kruger N, Leendertz FH, Ndhatz-Sanogo M, Schaumburg F, Witkowski PT, Akoua-Koffi CG, Kruger DH. Human Infections by Non-Rodent-Associated Hantaviruses in Africa. J Infect Dis. 2016 Nov 15;214(10):1507-1511. [Abstract]
13. Huson MAM, Hoogendijk AJ, de Vos AF, Grobusch MP, van der Poll T. The impact of HIV infection on blood leukocyte responsiveness to bacterial stimulation in asymptomatic patients and patients with bloodstream infection. J Int AIDS Soc. 2016 May 16;19(1):20759. [Abstract] [Free Full Article]
14. Huson MAM, Kalkman R, Grobusch MP, van der Poll T. Predictive value of the qSOFA score in patients with suspected infection in a resource limited setting in Gabon. Travel Med Infect Dis. 2017 Jan - Feb;15:76-77. [Abstract]
15. Huson MAM, Kalkman R, Hoogendijk AJ, Alabi AS, van 't Veer C, Grobusch MP, Meijers JC, van der Poll T. Impact of HIV infection on the haemostatic response during sepsis and malaria. Br J Haematol. 2016 Jun;173(6):918-26. [Abstract]
16. Ippolito G, Lanini S, Brouqui P, Di Caro A, Vairo F, Fusco FM, Krishna S, Capobianchi MR, Kyobe-Bosa H, Puro V, Wölfel R, Avsic-Zupanc T, Ioannidis JP, Portella G, Kremsner P, Dar O, Bates M, Zumla A. Non-randomised Ebola trials-lessons for optimal outbreak research. Lancet Infect Dis. 2016 Apr;16(4):407-8. [Abstract]
17. Kabaghe AN, Visser BJ, Spijker R, Phiri KS, Grobusch MP, van Vugt M. Health workers' compliance to rapid diagnostic tests (RDTs) to guide malaria treatment: a systematic review and meta-analysis. Malar J. 2016 Mar 15;15(1):163. [Abstract] [Free Full Article]
18. Kremsner PG, Adegnika AA, Hounkpatin AB, Zinsou JF, Taylor TE, Chimalizeni Y, Liomba A, Kombila M, Bouyou-Akotet MK, Mawili Mboumba DP, Agbenyega T, Ansong D, Sylverken J, Ogutu BR, Otieno GA, Wangwe A, Bojang KA, Okomo U, Sanya-Isijola F, Newton CR, Njuguna P, Kazungu M, Kerb R, Geditz M, Schwab M, Velavan TP, Nguetse C, Köhler C, Issifou S, Bolte S, Engleitner T, Mordmüller B, Krishna S. Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial. PLoS Med. 2016 Jan 12;13(1):e1001938. [Abstract] [Free Full Article]
19. Krishna S, Staines HM, Kremsner PG. Artemisinin Resistance and the Blame Game. Clin Infect Dis. 2016 Oct 15;63(8):1144-5. [Abstract]
20. Lötsch F, Obermüller M, Mischlinger J, Mombo-Ngoma G, Groger M, Adegnika AA, Agnandji ST, Schneider R, Auer H, Ramharter M. Seroprevalence of Toxocara spp. in a rural population in Central African Gabon. Parasitol Int. 2016 Dec;65(6 Pt A):632-634. [Abstract]
21. Maixenchs M, Anselmo R, Zielinski-Gutiérrez E, Odhiambo FO, Akello C, Ondire M, Zaidi SS, Soofi SB, Bhutta ZA, Diarra K, Djitèye M, Dembélé R, Sow S, Minsoko PC, Agnandji ST, Lell B, Ismail MR, Carrilho C, Ordi J, Menéndez C, Bassat Q, Munguambe K. Willingness to Know the Cause of Death and Hypothetical Acceptability of the Minimally Invasive Autopsy in Six Diverse African and Asian Settings: A Mixed Methods Socio-Behavioural Study. PLoS Med. 2016 Nov 22;13(11):e1002172. [Abstract] [Free Full Article]
22. Manabe YC, Worodria W, van Leth F, Mayanja-Kizza H, Traore AN, Ferro J, Pakker N, Frank M, Grobusch MP, Colebunders R, Cobelens F. Prevention of Early Mortality by Presumptive Tuberculosis Therapy Study: An Open Label, Randomized Controlled Trial. Am J Trop Med Hyg. 2016 Dec 7;95(6):1265-1271. [Abstract] [Free Full Article]
23. Mischlinger J, Agnandji ST, Ramharter M. Single dose treatment of malaria - current status and perspectives. Expert Rev Anti Infect Ther. 2016 Jun 2. [Abstract]
24. Moekotte AL, Huson MA, van der Ende AJ, Agnandji ST, Huizenga E, Goorhuis A, Grobusch MP. Monoclonal antibodies for the treatment of Ebola virus disease. Expert Opin Investig Drugs. 2016 Nov;25(11):1325-1335. [Abstract]
25. Mombo-Ngoma G, Honkpehedji J, Basra A, Mackanga JR, Zoleko RM, Zinsou J, Agobe JC, Lell B, Matsiegui PB, Gonzales R, Agnandji ST, Yazdanbakhsh M, Menendez C, Kremsner PG, Adegnika AA, Ramharter M. Urogenital schistosomiasis during pregnancy is associated with low birth weight delivery: analysis of a prospective cohort of pregnant women and their offspring in Gabon. Int J Parasitol. 2017 Jan;47(1):69-74. [Abstract]
26. Mombo-Ngoma G, Mackanga JR, González R, Ouedraogo S, Kakolwa MA, Manego RZ, Basra A, Rupérez M, Cot M, Kabanywany AM, Matsiegui PB, Agnandji ST, Vala A, Massougbodji A, Abdulla S, Adegnika AA, Sevene E, Macete E, Yazdanbakhsh M, Kremsner PG, Aponte JJ, Menéndez C, Ramharter M. Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study. BMJ Open. 2016 Jun 29;6(6):e011783. [Abstract] [Free Full Article]
27. Nguetse CN, Meyer CG, Adegnika AA, Agbenyega T, Ogutu BR, Kremsner PG, Velavan TP. Glucose-6-phosphate dehydrogenase deficiency and reduced haemoglobin levels in African children with severe malaria. Malar J. 2016 Jul 7;15(1):346. [Abstract] [Free Full Article]
28. Okuda KV, Toepfner N, Alabi AS, Arnold B, Bélard S, Falke U, Menschner L, Monecke S, Ruppelt-Lorz A, Berner R. Molecular epidemiology of Staphylococcus aureus from Lambaréné, Gabon. Eur J Clin Microbiol Infect Dis. 2016 Dec;35(12):1963-1973. [Abstract]
29. Rehman K, Sauerzopf U, Veletzky L, Lötsch F, Groger M, Ramharter M. Effect of mild medical hypothermia on in vitro growth of Plasmodium falciparum and the activity of anti-malarial drugs. Malar J. 2016 Mar 15;15(1):162. [Abstract] [Free Full Article]
30. Rupérez M, González R, Mombo-Ngoma G, Kabanywanyi AM, Sevene E, Ouédraogo S, Kakolwa MA, Vala A, Accrombessi M, Briand V, Aponte JJ, Manego Zoleko R, Adegnika AA, Cot M, Kremsner PG, Massougbodji A, Abdulla S, Ramharter M, Macete E, Menéndez C. Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study. PLoS Med. 2016 Feb 23;13(2):e1001964. [Abstract] [Free Full Article]
31. Schaumburg F, Peters G, Alabi A, Becker K, Idelevich EA. Missense mutations of PBP2a are associated with reduced susceptibility to ceftaroline and ceftobiprole in African MRSA. J Antimicrob Chemother. 2016 Jan;71(1):41-4. [Abstract]
32. Sirima SB, Mordmüller B, Milligan P, Ngoa UA, Kironde F, Atuguba F, Tiono AB, Issifou S, Kaddumukasa M, Bangre O, Flach C, Christiansen M, Bang P, Chilengi R, Jepsen S, Kremsner PG, Theisen M; GMZ2 Trial Study Group. A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children. Vaccine. 2016 Aug 31;34(38):4536-42. [Abstract]
33. Strauß L, Ruffing U, Abdulla S, Alabi A, Akulenko R, Garrine M, Germann A, Grobusch MP, Helms V, Herrmann M, Kazimoto T, Kern W, Mandomando I, Peters G, Schaumburg F, von Müller L, Mellmann A. Detecting Staphylococcus aureus Virulence and Resistance Genes: a Comparison of Whole-Genome Sequencing and DNA Microarray Technology. J Clin Microbiol. 2016 Apr;54(4):1008-16. [Abstract] [Free Full Article]
34. Visser BJ, de Vries SG, Bache EB, Meerveld-Gerrits J, Kroon D, Boersma J, Agnandji ST, van Vugt M, Grobusch MP. The diagnostic accuracy of the hand-held Raman spectrometer for the identification of anti-malarial drugs. Malar J. 2016 Mar 15;15(1):160. [Abstract] [Free Full Article]
35. WWARN Gametocyte Study Group. Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data. BMC Med. 2016 May 24;14:79. [Abstract] [Free Full Article]