Scientific Publications 2014
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Adegnika AA, Zinsou JF, Issifou S, Ateba-Ngoa U, Kassa RF, Feugap EN,
Honkpehedji YJ, Dejon Agobe JC, Kenguele HM, Massinga-Loembe M, Agnandji ST,
Mordmüller B, Ramharter M, Yazdanbakhsh M, Kremsner PG, Lell B. Randomized,
controlled, assessor-blind clinical trial to assess the efficacy of single-
versus repeated-dose albendazole to treat ascaris lumbricoides, trichuris
trichiura, and hookworm infection. Antimicrob Agents Chemother. 2014
May;58(5):2535-40.
[Abstract]
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Ateba Ngoa U, Zinsou JF, Kassa RF, Ngoune Feugap E, Honkpehedji YJ,
Massinga-Loembe M, Kenguele Moundounga H, Nkoma Mouima AM, Mbenkep LH, Wammes LJ,
Mbow M, Kruize Y, Mombo-Ngoma G, Bouyoukou Hounkpatin AL, Dejon Agobe JC, Saadou
I, Lell B, Smits H, Kremsner PG, Yazdanbakhsh M, Adegnika AA. Assessment of the
effect of Schistosoma haematobium co infection on malaria parasites and immune
responses in rural populations in Gabon: study protocol. Springerplus. 2014 Jul
29;3:388.
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Ateba-Ngoa U, Mombo-Ngoma G, Zettlmeissl E, van der Vlugt LE, de Jong S,
Matsiegui PB, Ramharter M, Kremsner PG, Yazdanbakhsh M, Adegnika AA.
CD4+CD25hiFOXP3+ cells in cord blood of neonates born from filaria infected
mother are negatively associated with CD4+Tbet+ and CD4+RORγt+ T cells. PLoS One.
2014 Dec 22;9(12):e114630.
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Auer-Hackenberg L, Thol F, Akerey-Diop D, Zoleko RM, Rodolphe Mackanga J,
Adegnika AA, Mombo-Ngoma G, Ramharter M. Short report: premastication in rural
Gabon--a cross-sectional survey. J Trop Pediatr. 2014 Apr;60(2):154-6.
[Abstract]
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Bélard S, Janssen S, Osbak KK, Adegnika AA, Ondounda M, Grobusch MP. Limited
access to drugs for resistant tuberculosis: a call to action. J Public Health
(Oxf). 2014 Dec 19. pii: fdu101.
[Abstract]
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Bélard S, Toepfner N, Arnold B, Alabi AS, Berner R. β-hemolytic streptococcal
throat carriage and tonsillopharyngitis: a cross-sectional prevalence study in
Gabon, Central Africa. Infection. 2014 Nov 28.
[Abstract]
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Flamen A, Bélard S, Kokou C, Janssen S, Grobusch MP. Childhood tuberculosis in
Lambaréné, Gabon: tuberculosis control in its infancy? Infection. 2014
Feb;42(1):161-4.
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Gehringer C, Kreidenweiss A, Flamen A, Antony JS, Grobusch MP, Bélard S.
Molecular evidence of Wolbachia endosymbiosis in Mansonella perstans in Gabon,
Central Africa. J Infect Dis. 2014 Nov 15;210(10):1633-8.
[Abstract]
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González R, Mombo-Ngoma G, Ouédraogo S, Kakolwa MA, Abdulla S, Accrombessi M,
Aponte JJ, Akerey-Diop D, Basra A, Briand V, Capan M, Cot M, Kabanywanyi AM,
Kleine C, Kremsner PG, Macete E, Mackanga JR, Massougbodgi A, Mayor A, Nhacolo A,
Pahlavan G, Ramharter M, Rupérez M, Sevene E, Vala A, Zoleko-Manego R, Menéndez
C. Intermittent preventive treatment of malaria in pregnancy with mefloquine in
HIV-negative women: a multicentre randomized controlled trial. PLoS Med. 2014 Sep
23;11(9):e1001733.
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Goovaerts O, Jennes W, Massinga-Loembé M, Ceulemans A, Worodria W,
Mayanja-Kizza H, Colebunders R, Kestens L; TB-IRIS Study Group. Antigen-specific
interferon-gamma responses and innate cytokine balance in TB-IRIS. PLoS One. 2014
Nov 21;9(11):e113101.
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Hänscheid T, Gresnigt T, Löhr S, Flamen A, Zoller T, Melo-Cristino J, Grobusch
MP. Methaemoglobin and COHb in patients with malaria. Malar J. 2014 Jul
23;13:285.
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Huson MA, Kalkman R, Remppis J, Beyeme JO, Kraef C, Schaumburg F, Alabi AS,
Grobusch MP. Methicillin-resistant Staphylococcus aureus as a cause of invasive
infections in Central Africa: a case report and review of the literature.
Infection. 2014 Jun;42(3):451-7.
[Abstract]
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Labuda LA, Ateba-Ngoa U, Feugap EN, Heeringa JJ, van der Vlugt LE, Pires RB,
Mewono L, Kremsner PG, van Zelm MC, Adegnika AA, Yazdanbakhsh M, Smits HH.
Alterations in peripheral blood B cell subsets and dynamics of B cell responses
during human schistosomiasis. PLoS Negl Trop Dis. 2013;7(3):e2094.
[Abstract]
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Kajungu DK, Erhart A, Talisuna AO, Bassat Q, Karema C, Nabasumba C, Nambozi M,
Tinto H, Kremsner P, Meremikwu M, D'Alessandro U, Speybroeck N. Paediatric
pharmacovigilance: use of pharmacovigilance data mining algorithms for signal
detection in a safety dataset of a paediatric clinical study conducted in seven
African countries. PLoS One. 2014 May 1;9(5):e96388.
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Kenguele HM, Adegnika AA, Nkoma AM, Ateba-Ngoa U, Mbong M, Zinsou J, Lell B,
Verweij JJ. Impact of short-time urine freezing on the sensitivity of an
established Schistosoma real-time PCR assay. Am J Trop Med Hyg. 2014
Jun;90(6):1153-5.
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Labuda LA, de Jong SE, Meurs L, Amoah AS, Mbow M, Ateba-Ngoa U, van der Ham
AJ, Knulst AC, Yazdanbakhsh M, Adegnika AA. Differences in innate cytokine
responses between European and African children. PLoS One. 2014 Apr
17;9(4):e95241.
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Metzger WG, Mordmüller B. Loa loa-does it deserve to be neglected? Lancet
Infect Dis. 2014 Apr;14(4):353-7.
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Nguetse CN, Kremsner PG, Velavan TP. FOXO3A regulatory polymorphism and
susceptibility to severe malaria in Gabonese children. Immunogenetics. 2015
Feb;67(2):67-71.
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Nurjadi D, Olalekan AO, Layer F, Shittu AO, Alabi A, Ghebremedhin B,
Schaumburg F, Hofmann-Eifler J, Van Genderen PJ, Caumes E, Fleck R, Mockenhaupt
FP, Herrmann M, Kern WV, Abdulla S, Grobusch MP, Kremsner PG, Wolz C, Zanger P.
Emergence of trimethoprim resistance gene dfrG in Staphylococcus aureus causing
human infection and colonization in sub-Saharan Africa and its import to Europe.
J Antimicrob Chemother. 2014 Sep;69(9):2361-8.
[Abstract]
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Ramharter M, Harrison N, Bühler T, Herold B, Lagler H, Lötsch F, Mombo-Ngoma
G, Müller C, Adegnika AA, Kremsner PG, Makristathis A. Prevalence and risk factor
assessment of Tropheryma whipplei in a rural community in Gabon: a
community-based cross-sectional study. Clin Microbiol Infect. 2014
Nov;20(11):1189-94.
[Abstract]
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Rehman K, Lötsch F, Kremsner PG, Ramharter M. Haemolysis associated with the
treatment of malaria with artemisinin derivatives: a systematic review of current
evidence. Int J Infect Dis. 2014 Dec;29:268-73.
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Rolling T, Agbenyega T, Issifou S, Adegnika AA, Sylverken J, Spahlinger D,
Ansong D, Löhr SJ, Burchard GD, May J, Mordmüller B, Krishna S, Kremsner PG,
Cramer JP. Delayed hemolysis after treatment with parenteral artesunate in
African children with severe malaria--a double-center prospective study. J Infect
Dis. 2014 Jun 15;209(12):1921-8.
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RTS,S Clinical Trials Partnership. Efficacy and safety of the RTS,S/AS01
malaria vaccine during 18 months after vaccination: a phase 3 randomized,
controlled trial in children and young infants at 11 African sites. PLoS Med.
2014 Jul 29;11(7):e1001685.
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Sauerzopf U, Honkpehedji YJ, Adgenika AA, Feugap EN, Ngoma GM, Mackanga JR,
Lötsch F, Loembe MM, Kremsner PG, Mordmüller B, Ramharter M. In vitro growth of
Plasmodium falciparum in neonatal blood. Malar J. 2014 Nov 18;13:436.
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Schaumburg F, Alabi AS, Kaba H, Lell B, Becker K, Grobusch MP, Kremsner PG,
Mellmann A. Molecular characterization of Shigella spp. from patients in Gabon
2011-2013. Trans R Soc Trop Med Hyg. 2014 Nov 20. pii: tru175.
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Schaumburg F, Alabi AS, Peters G, Becker K. New epidemiology of Staphylococcus
aureus infection in Africa. Clin Microbiol Infect. 2014 Jul;20(7):589-96.
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Schaumburg F, Alabi AS, Mombo-Ngoma G, Kaba H, Zoleko RM, Diop DA, Mackanga
JR, Basra A, Gonzalez R, Menendez C, Grobusch MP, Kremsner PG, Köck R, Peters G,
Ramharter M, Becker K. Transmission of Staphylococcus aureus between mothers and
infants in an African setting. Clin Microbiol Infect. 2014 Jun;20(6):O390-6.
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Schaumburg F, Alabi AS, Frielinghaus L, Grobusch MP, Köck R, Becker K, Issifou
S, Kremsner PG, Peters G, Mellmann A. The risk to import ESBL-producing
Enterobacteriaceae and Staphylococcus aureus through chicken meat trade in Gabon.
BMC Microbiol. 2014 Nov 19;14:286.
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Schaumburg F, Pauly M, Anoh E, Mossoun A, Wiersma L, Schubert G, Flammen A,
Alabi AS, Muyembe-Tamfum JJ, Grobusch MP, Karhemere S, Akoua-Koffi C,
Couacy-Hymann E, Kremsner PG, Mellmann A, Becker K, Leendertz FH, Peters G.
Staphylococcus aureus complex from animals and humans in three remote African
regions. Clin Microbiol Infect. 2014 Dec 11. pii: S1198-743X(14)00113-X.
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Scherbaum M, Kösters K, Mürbeth RE, Ngoa UA, Kremsner PG, Lell B, Alabi A.
Incidence, pathogens and resistance patterns of nosocomial infections at a rural
hospital in Gabon. BMC Infect Dis. 2014 Mar 4;14:124.
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Taylor SM, Mayor A, Mombo-Ngoma G, Kenguele HM, Ouédraogo S, Ndam NT, Mkali H,
Mwangoka G, Valecha N, Singh JP, Clark MA, Verweij JJ, Adegnika AA, Severini C,
Menegon M, Macete E, Menendez C, Cisteró P, Njie F, Affara M, Otieno K, Kariuki
S, ter Kuile FO, Meshnick SR. A quality control program within a clinical trial
Consortium for PCR protocols to detect Plasmodium species. J Clin Microbiol. 2014
Jun;52(6):2144-9.
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van der Vlugt LE, Zinsou JF, Ozir-Fazalalikhan A, Kremsner PG, Yazdanbakhsh M,
Adegnika AA, Smits HH. Interleukin 10 (IL-10)-producing CD1dhi regulatory B cells
from Schistosoma haematobium-infected individuals induce IL-10-positive T cells
and suppress effector T-cell cytokines. J Infect Dis. 2014 Oct 15;210(8):1207-16.
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White MT, Bejon P, Olotu A, Griffin JT, Bojang K, Lusingu J, Salim N, Abdulla
S, Otsyula N, Agnandji ST, Lell B, Asante KP, Owusu-Agyei S, Mahama E, Agbenyega
T, Ansong D, Sacarlal J, Aponte JJ, Ghani AC. A combined analysis of
immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the
RTS,S malaria vaccine. BMC Med. 2014 Jul 10;12:117.
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Zaloumis SG, Tarning J, Krishna S, Price RN, White NJ, Davis TM, McCaw JM,
Olliaro P, Maude RJ, Kremsner P, Dondorp A, Gomes M, Barnes K, Simpson JA.
Population pharmacokinetics of intravenous artesunate: a pooled analysis of
individual data from patients with severe malaria. CPT Pharmacometrics Syst
Pharmacol. 2014 Nov 5;3:e145.
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