Publications scientifiques 2017
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Agnandji ST, Fernandes JF, Bache EB, Obiang Mba RM, Brosnahan JS, Kabwende L,
Pitzinger P, Staarink P, Massinga-Loembe M, Krähling V, Biedenkopf N, Fehling SK,
Strecker T, Clark DJ, Staines HM, Hooper JW, Silvera P, Moorthy V, Kieny MP,
Adegnika AA, Grobusch MP, Becker S, Ramharter M, Mordmüller B, Lell B; VEBCON
Consortium, Krishna S, Kremsner PG. Safety and immunogenicity of rVSVΔG-ZEBOV-GP
Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised
trial. PLoS Med. 2017 Oct 6;14(10):e1002402.
[Abstract]
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Alabi AS, Traoré AN, Loembe MM, Ateba-Ngoa U, Frank M, Adegnika AA, Lell B,
Mahoumbou J, Köhler C, Kremsner PG, Grobusch MP; CERMEL TB CapDev Group. Enhanced
laboratory capacity development: a boost for effective tuberculosis control in
resource-limited settings. Int J Infect Dis. 2017 Mar;56:81-84.
[Abstract]
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Boström S, Schmiegelow C, Abu Abed U, Minja DTR, Lusingu J, Brinkmann V,
Honkpehedji YJ, Loembe MM, Adegnika AA, Mordmüller B, Troye-Blomberg M, Amulic B.
Neutrophil alterations in pregnancy-associated malaria and induction of
neutrophil chemotaxis by Plasmodium falciparum. Parasite Immunol. 2017 Jun;39(6).
[Abstract]
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Dejaco D, Aregger FC, Hurth HV, Kegele J, Muigg V, Oberhammer L, Bunk S,
Fischer N, Pinggera L, Riedl D, Otieno A, Agbenyega T, Adegnika AA, Riechelmann
H, Lackner P, Zorowka P, Kremsner P, Schmutzhard J. Evaluation of
transient-evoked otoacoustic emissions in a healthy 1 to 10 year pediatric cohort
in Sub-Saharan Africa. Int J Pediatr Otorhinolaryngol. 2017 Oct;101:65-69
[Abstract]
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Ehrhardt J, Alabi AS, Kremsner PG, Rabsch W, Becker K, Foguim FT, Kuczius T,
Esen M, Schaumburg F. Bacterial contamination of water samples in Gabon, 2013. J
Microbiol Immunol Infect. 2017 Oct;50(5):718-722.
[Abstract]
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Gebru T, Ajua A, Theisen M, Esen M, Ngoa UA, Issifou S, Adegnika AA, Kremsner
PG, Mordmüller B, Held J. Recognition of Plasmodium falciparum mature
gametocyte-infected erythrocytes by antibodies of semi-immune adults and
malaria-exposed children from Gabon. Malar J. 2017 Apr 26;16(1):176.
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Held J, Supan C, Salazar CLO, Tinto H, Bonkian LN, Nahum A, Sié A, Abdulla S,
Cantalloube C, Djeriou E, Bouyou-Akotet M, Ogutu B, Mordmüller B, Kreidenweiss A,
Siribie M, Sirima SB, Kremsner PG. Safety and efficacy of the choline analogue
SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter
trials in African patients. Malar J. 2017 May 4;16(1):188.
[Abstract]
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Huson MA, Kalkman R, Grobusch MP, van der Poll T. Predictive value of the
qSOFA score in patients with suspected infection in a resource limited setting in
Gabon. Travel Med Infect Dis. 2017 Jan - Feb;15:76-77.
[Abstract]
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Huttner A, Combescure C, Grillet S, Haks MC, Quinten E, Modoux C, Agnandji ST,
Brosnahan J, Dayer JA, Harandi AM, Kaiser L, Medaglini D, Monath T; VEBCON and
VSV-EBOVAC Consortia, Roux-Lombard P, Kremsner PG, Ottenhoff TH, Siegrist CA. A
dose-dependent plasma signature of the safety and immunogenicity of the
rVSV-Ebola vaccine in Europe and Africa. Sci Transl Med. 2017 Apr 12;9(385). pii:
eaaj1701.
[Abstract]
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Janssen S, Huson MA, Osbak KK, Rossatanga EG, Alabi A, Lutter R, Grobusch MP,
van der Poll T. HIV infection rather than concurrent opportunistic infections
drives most systemic procoagulant, vascular and damage responses - a prospective
cohort study in central Africa. Antivir Ther. 2017;22(2):153-161.
[Abstract]
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Janssen S, Osbak K, Holman R, Hermans S, Moekotte A, Knap M, Rossatanga E,
Massinga-Loembe M, Alabi A, Adegnika A, Meenken C, van Vugt M, Kremsner PG,
Meintjes G, van der Poll T, Grobusch MP. Low incidence of the immune
reconstitution inflammatory syndrome among HIV-infected patients starting
antiretroviral therapy in Gabon: a prospective cohort study. Infection. 2017
Oct;45(5):669-676.
[Abstract]
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Lalremruata A, Jeyaraj S, Engleitner T, Joanny F, Lang A, Bélard S,
Mombo-Ngoma G, Ramharter M, Kremsner PG, Mordmüller B, Held J. Species and
genotype diversity of Plasmodium in malaria patients from Gabon analysed by next
generation sequencing. Malar J. 2017 Oct 3;16(1):398.
[Abstract]
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Macintyre F, Adoke Y, Tiono AB, Duong TT, Mombo-Ngoma G, Bouyou-Akotet M,
Tinto H, Bassat Q, Issifou S, Adamy M, Demarest H, Duparc S, Leroy D, Laurijssens
BE, Biguenet S, Kibuuka A, Tshefu AK, Smith M, Foster C, Leipoldt I, Kremsner PG,
Phuc BQ, Ouedraogo A, Ramharter M; OZ-Piperaquine Study Group. A randomised,
double-blind clinical phase II trial of the efficacy, safety, tolerability and
pharmacokinetics of a single dose combination treatment with artefenomel and
piperaquine in adults and children with uncomplicated Plasmodium falciparum
malaria. BMC Med. 2017 Oct 9;15(1):181.
[Abstract]
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Manego RZ, Mombo-Ngoma G, Witte M, Held J, Gmeiner M, Gebru T, Tazemda B,
Mischlinger J, Groger M, Lell B, Adegnika AA, Agnandji ST, Kremsner PG,
Mordmüller B, Ramharter M, Matsiegui PB. Demography, maternal health and the
epidemiology of malaria and other major infectious diseases in the rural
department Tsamba-Magotsi, Ngounie Province, in central African Gabon. BMC Public
Health. 2017 Jan 28;17(1):130.
[Abstract]
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Mombo-Ngoma G, Honkpehedji J, Basra A, Mackanga JR, Zoleko RM, Zinsou J, Agobe
JC, Lell B, Matsiegui PB, Gonzales R, Agnandji ST, Yazdanbakhsh M, Menendez C,
Kremsner PG, Adegnika AA, Ramharter M. Urogenital schistosomiasis during
pregnancy is associated with low birth weight delivery: analysis of a prospective
cohort of pregnant women and their offspring in Gabon. Int J Parasitol. 2017
Jan;47(1):69-74.
[Abstract]
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Moncunill G, Mpina M, Nhabomba AJ, Aguilar R, Ayestaran A, Sanz H, Campo JJ,
Jairoce C, Barrios D, Dong Y, Díez-Padrisa N, Fernandes JF, Abdulla S, Sacarlal
J, Williams NA, Harezlak J, Mordmüller B, Agnandji ST, Aponte JJ, Daubenberger C,
Valim C, Dobaño C. Distinct Helper T Cell Type 1 and 2 Responses Associated With
Malaria Protection and Risk in RTS,S/AS01E Vaccinees. Clin Infect Dis. 2017 Sep
1;65(5):746-755.
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Mutters NT, Malek V, Agnandji ST, Günther F, Tacconelli E. Evaluation of the
scientific impact of the Ebola epidemic: a systematic review. Clin Microbiol
Infect. 2018 Jun;24(6):573-576.
[Abstract]
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Ndam NT, Mbuba E, González R, Cisteró P, Kariuki S, Sevene E, Rupérez M,
Fonseca AM, Vala A, Maculuve S, Jiménez A, Quintó L, Ouma P, Ramharter M, Aponte
JJ, Nhacolo A, Massougbodji A, Briand V, Kremsner PG, Mombo-Ngoma G, Desai M,
Macete E, Cot M, Menéndez C, Mayor A. Resisting and tolerating P. falciparum in
pregnancy under different malaria transmission intensities. BMC Med. 2017 Jul
17;15(1):130.
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Nguetse CN, Adegnika AA, Agbenyega T, Ogutu BR, Krishna S, Kremsner PG,
Velavan TP. Molecular markers of anti-malarial drug resistance in Central, West
and East African children with severe malaria. Malar J. 2017 May 23;16(1):217.
[Abstract]
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Ruffing U, Alabi A, Kazimoto T, Vubil DC, Akulenko R, Abdulla S, Alonso P,
Bischoff M, Germann A, Grobusch MP, Helms V, Hoffmann J, Kern WV, Kremsner PG,
Mandomando I, Mellmann A, Peters G, Schaumburg F, Schubert S, Strauß L, Tanner M,
Briesen HV, Wende L, Müller LV, Herrmann M. Community-Associated Staphylococcus
aureus from Sub-Saharan Africa and Germany: A Cross-Sectional Geographic
Correlation Study. Sci Rep. 2017 Mar 13;7(1):154.
[Abstract]
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Supan C, Mombo-Ngoma G, Kombila M, Ospina Salazar CL, Held J, Lell B,
Cantalloube C, Djeriou E, Ogutu B, Waitumbi J, Otsula N, Apollo D, Polhemus ME,
Kremsner PG, Walsh DS. Phase 2a, Open-Label, 4-Escalating-Dose, Randomized
Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193)
Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with
Uncomplicated Plasmodium falciparum Malaria. Am J Trop Med Hyg. 2017
Aug;97(2):514-525.
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Triller G, Scally SW, Costa G, Pissarev M, Kreschel C, Bosch A, Marois E, Sack
BK, Murugan R, Salman AM, Janse CJ, Khan SM, Kappe SHI, Adegnika AA, Mordmüller
B, Levashina EA, Julien JP, Wardemann H. Natural Parasite Exposure Induces
Protective Human Anti-Malarial Antibodies. Immunity. 2017 Dec
19;47(6):1197-1209.e10.
[Abstract]
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Visser BJ, de Vries SG, Vingerling R, Gritter M, Kroon D, Aguilar LC, Kraan
RBJ, Wieten RW, Danion F, Sjouke B, Adegnika AA, Agnandji ST, Kremsner PG,
Hänscheid T, Mens PF, van Vugt M, Grobusch MP. Serum Lipids and Lipoproteins
During Uncomplicated Malaria: A Cohort Study in Lambaréné, Gabon. Am J Trop Med
Hyg. 2017 May;96(5):1205-1214.
[Abstract]
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