Publications

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Scientific Publications 2011 [View all on PubMed]

  • Adegnika AA, Luty AJ, Grobusch MP, Ramharter M, Yazdanbakhsh M, Kremsner PG, Schwarz NG. ABO blood group and the risk of placental malaria in sub-Saharan Africa. Malar J. 2011 Apr 22;10:101. [Abstract] [Free Full Article]

  • Agnandji ST, Fendel R, Mestré M, Janssens M, Vekemans J, Held J, Gnansounou F, Haertle S, von Glasenapp I, Oyakhirome S, Mewono L, Moris P, Lievens M, Demoitie MA, Dubois PM, Villafana T, Jongert E, Olivier A, Cohen J, Esen M, Kremsner PG, Lell B, Mordmüller B. Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D). PLoS One. 2011 Apr 11;6(4):e18559. [Abstract] [Free Full Article]

  • Agnandji ST, Kurth F, Bélard S, Mombo-Ngoma G, Basra A, Fernandes JF, Soulanoudjingar SS, Adegnika AA, Ramharter M. Current status of the clinical development and implementation of paediatric artemisinin combination therapies in Sub-Saharan Africa. Wien Klin Wochenschr. 2011 Oct;123 Suppl 1:7-9. [Abstract]

  • Agnandji ST, Kurth F, Fernandes JF, Soulanoudjingar SS, Abossolo BP, Mombo-Ngoma G, Basra A, González R, Kizito G, Mayengue PI, Auer-Hackenberg L, Issifou S, Lell B, Adegnika AA, Ramharter M. The use of paediatric artemisinin combinations in sub-Saharan Africa: a snapshot questionnaire survey of health care personnel. Malar J. 2011 Dec 14;10:365. [Abstract] [Free Full Article]

  • Agnandji ST, Lell B, Soulanoudjingar SS, Fernandes JF, Abossolo BP, Conzelmann C, Methogo BG, Doucka Y, Flamen A, Mordmüller B, Issifou S, Kremsner PG, Sacarlal J, Aide P, Lanaspa M, Aponte JJ, Nhamuave A, Quelhas D, Bassat Q, Mandjate S, Macete E, Alonso P, Abdulla S, Salim N, Juma O, Shomari M, Shubis K, Machera F, Hamad AS, Minja R, Mtoro A, Sykes A, Ahmed S, Urassa AM, Ali AM, Mwangoka G, Tanner M, Tinto H, D'Alessandro U, Sorgho H, Valea I, Tahita MC, Kaboré W, Ouédraogo S, Sandrine Y, Guiguemdé RT, Ouédraogo JB, Hamel MJ, Kariuki S, Odero C, Oneko M, Otieno K, Awino N, Omoto J, Williamson J, Muturi-Kioi V, Laserson KF, Slutsker L, Otieno W, Otieno L, Nekoye O, Gondi S, Otieno A, Ogutu B, Wasuna R, Owira V, Jones D, Onyango AA, Njuguna P, Chilengi R, Akoo P, Kerubo C, Gitaka J, Maingi C, Lang T, Olotu A, Tsofa B, Bejon P, Peshu N, Marsh K, Owusu-Agyei S, Asante KP, Osei-Kwakye K, Boahen O, Ayamba S, Kayan K, Owusu-Ofori R, Dosoo D, Asante I, Adjei G, Adjei G, Chandramohan D, Greenwood B, Lusingu J, Gesase S, Malabeja A, Abdul O, Kilavo H, Mahende C, Liheluka E, Lemnge M, Theander T, Drakeley C, Ansong D, Agbenyega T, Adjei S, Boateng HO, Rettig T, Bawa J, Sylverken J, Sambian D, Agyekum A, Owusu L, Martinson F, Hoffman I, Mvalo T, Kamthunzi P, Nkomo R, Msika A, Jumbe A, Chome N, Nyakuipa D, Chintedza J, Ballou WR, Bruls M, Cohen J, Guerra Y, Jongert E, Lapierre D, Leach A, Lievens M, Ofori-Anyinam O, Vekemans J, Carter T, Leboulleux D, Loucq C, Radford A, Savarese B, Schellenberg D, Sillman M, Vansadia P; RTS,S Clinical Trials Partnership. First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children. N Engl J Med. 2011 Nov 17;365(20):1863-75. [Abstract]

  • Asante KP, Abdulla S, Agnandji S, Lyimo J, Vekemans J, Soulanoudjingar S, Owusu R, Shomari M, Leach A, Jongert E, Salim N, Fernandes JF, Dosoo D, Chikawe M, Issifou S, Osei-Kwakye K, Lievens M, Paricek M, Möller T, Apanga S, Mwangoka G, Dubois MC, Madi T, Kwara E, Minja R, Hounkpatin AB, Boahen O, Kayan K, Adjei G, Chandramohan D, Carter T, Vansadia P, Sillman M, Savarese B, Loucq C, Lapierre D, Greenwood B, Cohen J, Kremsner P, Owusu-Agyei S, Tanner M, Lell B. Safety and efficacy of the RTS,S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial. Lancet Infect Dis. 2011 Oct;11(10):741-9. [Abstract]

  • Bélard S, Issifou S, Hounkpatin AB, Schaumburg F, Ngoa UA, Esen M, Fendel R, de Salazar PM, Mürbeth RE, Milligan P, Imbault N, Imoukhuede EB, Theisen M, Jepsen S, Noor RA, Okech B, Kremsner PG, Mordmüller B. A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children.PLoS One. 2011;6(7):e22525. [Abstract] [Free Full Article]

  • Enderes C, Kombila D, Dal-Bianco M, Dzikowski R, Kremsner P, Frank M. Var Gene promoter activation in clonal Plasmodium falciparum isolates follows a hierarchy and suggests a conserved switching program that is independent of genetic background. J Infect Dis. 2011 Nov 15;204(10):1620-31. [Abstract]

  • Faik I, Oyedeji SI, Idris Z, de Messias-Reason IJ, Lell B, Kremsner PG, Kun JF. Ficolin-2 levels and genetic polymorphisms of FCN2 in malaria. Hum Immunol. 2011 Jan;72(1):74-9. [Abstract]

  • Four Artemisinin-Based Combinations (4ABC) Study Group. A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial. PLoS Med. 2011 Nov;8(11):e1001119. [Abstract] [Free Full Article]

  • Frank M, Lehners N, Mayengue PI, Gabor J, Dal-Bianco M, Kombila DU, Ngoma GM, Supan C, Lell B, Ntoumi F, Grobusch MP, Dietz K, Kremsner PG. A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon. Malar J. 2011 Oct 17;10:304. [Abstract] [Free Full Article]

  • Hanel SA, Velavan TP, Kremsner PG, Kun JF. Novel and functional regulatory SNPs in the promoter region of FOXP3 gene in a Gabonese population.Immunogenetics. 2011 Jul;63(7):409-15. [Abstract]

  • Held J, Soomro SA, Kremsner PG, Jansen FH, Mordmüller B. In vitro activity of new artemisinin derivatives against Plasmodium falciparum clinical isolates from Gabon. Int J Antimicrob Agents. 2011 May;37(5):485-8. [Abstract]

  • Hogewoning AA, Adegnika AA, Bouwes Bavinck JN, Yazdanbakhsh M, Kremsner PG, Van der Raaij-Helmer EM, Staats CC, Willemze R, Lavrijsen AP. Prevalence and causative fungal species of tinea capitis among schoolchildren in Gabon. Mycoses. 2011 Sep;54(5):e354-9. [Abstract]

  • Hogewoning AA, Bouwes Bavinck JN, Amoah AS, Boakye DA, Yazdanbakhsh M, Kremsner PG, Adegnika AA, De Smedt SK, Willemze R, Lavrijsen AP. Point and period prevalences of eczema in rural and urban schoolchildren in Ghana, Gabon and Rwanda. J Eur Acad Dermatol Venereol. 2012 Apr;26(4):488-494. [Abstract]

  • Humberg A, Kammer J, Mordmüller B, Kremsner PG, Lell B. Haematological and biochemical reference intervals for infants and children in Gabon. Trop Med Int Health. 2011 Mar;16(3):343-8. [Abstract]

  • Köhler C, Adegnika AA, Van der Linden R, Luty AJ, Kremsner PG. Phenotypic characterization of mononuclear blood cells from pregnant Gabonese and their newborns. Trop Med Int Health. 2011 Sep;16(9):1061-9. [Abstract]

  • Kremsner PG, Taylor T, Issifou S, Kombila M, Chimalizeni Y, Kawaza K, Bouyou Akotet MK, Duscha M, Mordmüller B, Kösters K, Humberg A, Miller RS, Weina P, Duparc S, Möhrle J, Kun JF, Planche T, Teja-Isavadharm P, Simpson JA, Köhler C, Krishna S. A simplified intravenous artesunate regimen for severe malaria.J Infect Dis. 2012 Jan 15;205(2):312-9. [Abstract]

  • Kurth F, Bélard S, Basra A, Ramharter M. Pyronaridine: a new 'old' drug on the verge of entering the antimalarial armamentarium. Expert Rev Anti Infect Ther. 2011 Apr;9(4):393-6. [Abstract]

  • Kurth F, Bélard S, Basra A, Ramharter M. Pyronaridine-artesunate combination therapy for the treatment of malaria. Curr Opin Infect Dis. 2011 Dec;24(6):564-9. Review. [Abstract]

  • Lenz D, Kremsner PG, Lell B, Biallas B, Boettcher M, Mordmüller B, Adegnika AA. Assessment of LED fluorescence microscopy for the diagnosis of Plasmodium falciparum infections in Gabon. Malar J. 2011 Jul 18;10:194. [Abstract] [Free Full Article]

  • Meurs L, Labuda L, Amoah AS, Mbow M, Ngoa UA, Boakye DA, Mboup S, Dièye TN, Mountford AP, Turner JD, Kremsner PG, Polman K, Yazdanbakhsh M, Adegnika AA. Enhanced pro-inflammatory cytokine responses following Toll-like-receptor ligation in Schistosoma haematobium-infected schoolchildren from rural Gabon. PLoS One. 2011;6(9):e24393. [Abstract] [Free Full Article]

  • Mombo-Ngoma G, Oyakhirome S, Ord R, Gabor JJ, Greutélaers KC, Profanter K, Greutélaers B, Kurth F, Lell B, Kun JF, Issifou S, Roper C, Kremsner PG, Grobusch MP. High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children. Malar J. 2011 May 14;10:123. [Abstract] [Free Full Article]

  • Mombo-Ngoma G, Supan C, Dal-Bianco MP, Missinou MA, Matsiegui PB, Ospina Salazar CL, Issifou S, Ter-Minassian D, Ramharter M, Kombila M, Kremsner PG, Lell B. Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection. Malar J. 2011 Mar 1;10:53. [Abstract] [Free Full Article]

  • Nemeth J, Winkler HM, Boeck L, Adegnika AA, Clement E, Mve TM, Kremsner PG, Winkler S. Specific cytokine patterns of pulmonary tuberculosis in Central Africa. Clin Immunol. 2011 Jan;138(1):50-9. [Abstract]

  • Pongratz P, Kurth F, Ngoma GM, Basra A, Ramharter M. In vitro activity of antifungal drugs against Plasmodium falciparum field isolates. Wien Klin Wochenschr. 2011 Oct;123 Suppl 1:26-30. [Abstract]

  • Schaumburg F, Köck R, Friedrich AW, Soulanoudjingar S, Ngoa UA, von Eiff C, Issifou S, Kremsner PG, Herrmann M, Peters G, Becker K. Population structure of Staphylococcus aureus from remote African Babongo Pygmies. PLoS Negl Trop Dis. 2011 May 10;5(5):e1150. [Abstract] [Free Full Article]

  • Schaumburg F, Ngoa UA, Kösters K, Köck R, Adegnika AA, Kremsner PG, Lell B, Peters G, Mellmann A, Becker K. Virulence factors and genotypes of Staphylococcus aureus from infection and carriage in Gabon. Clin Microbiol Infect. 2011 Oct;17(10):1507-13. [Abstract]

  • Selman MH, de Jong SE, Soonawala D, Kroon FP, Adegnika AA, Deelder AM, Hokke CH, Yazdanbakhsh M, Wuhrer M. Changes in Antigen-specific IgG1 Fc N-glycosylation Upon Influenza and Tetanus Vaccination. Mol Cell Proteomics. 2012 Apr;11(4):M111.014563. [Abstract] [Free Full Article]

  • Sicuri E, Biao P, Hutton G, Tediosi F, Menendez C, Lell B, Kremsner P, Conteh L, Grobusch MP. Cost-effectiveness of intermittent preventive treatment of malaria in infants (IPTi) for averting anaemia in Gabon: a comparison between intention to treat and according to protocol analyses. Malar J. 2011 Oct 17;10:305. [Abstract] [Free Full Article]

  • Swysen C, Vekemans J, Bruls M, Oyakhirome S, Drakeley C, Kremsner P, Greenwood B, Ofori-Anyinam O, Okech B, Villafana T, Carter T, Savarese B, Duse A, Reijman A, Ingram C, Frean J, Ogutu B; Clinical Trials Partnership Committee. Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine. Malar J. 2011 Aug 4;10:223. [Abstract] [Free Full Article]

  • Van Vugt M, Van Beest A, Sicuri E, Van Tulder M, Grobusch MP. Malaria treatment and prophylaxis in endemic and nonendemic countries: evidence on strategies and their cost-effectiveness. Future Microbiol. 2011 Dec;6(12):1485-500. [Abstract]

  • Velavan TP, Bechlars S, Huang X, Kremsner PG, Kun JF. Novel regulatory SNPs in the promoter region of the TNFRSF18 gene in a Gabonese population. Braz J Med Biol Res. 2011 May;44(5):418-20. [Abstract]

  • Velavan TP, Bechlars S, Tomiuk J, Kremsner PG, Kun JF. Molecular characterization of regulatory polymorphisms in the promoter region of the STAT6 gene in a Gabonese population. Mem Inst Oswaldo Cruz. 2011 Feb;106(1):65-9. [Abstract]

  • Velavan TP, Büyükyazici B, Kremsner PG, Kun JF. Combined promoter haplotypes of the IL10R genes are associated with protection against severe malaria in Gabonese children. Immunogenetics. 2012 Feb;64(2):87-95. [Abstract]